Biomarkers

Cardiovascular Health: Current Treatments and Emerging Perspectives

Cardiovascular disease (CVD) remains the leading global cause of death despite decades of medical advancements. While traditional therapies like statins, beta-blockers, and surgical interventions have been lifesaving, evolving science and a deeper understanding of disease mechanisms are shifting the focus toward novel approaches. Here, we explore why the future of cardiovascular care requires innovation beyond the conventional and the critical paradigm shifts necessary to reshape how we prevent and manage heart disease.

by gip

Published: 25 July 2025

Read Time: 16:15

Limitations of Traditional Approaches

  1. Statins and the Cholesterol-Centric Model:
    • For decades, statins have been the cornerstone of lipid management. While they effectively reduce LDL cholesterol and cardiovascular events, they do not address the inflammatory components of atherosclerosis or the individual variations in lipid metabolism.
    • The cholesterol-centric model oversimplifies cardiovascular risk. Many patients on statins still experience significant events, suggesting that targeting LDL alone is insufficient.
  2. Reactive, Not Preventive:
    • Conventional care often waits for disease manifestation—whether it’s hypertension, angina, or a cardiac event—before intervening. This reactive approach misses opportunities for early detection and prevention.
    • Risk factors like chronic inflammation, oxidative stress, and insulin resistance often go unaddressed in traditional protocols, leaving key drivers of disease progression untreated.

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References

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